BMI-200B Microscope Incubator

BMI-200 Microscope Incubator is an intuitive and integrated system for live cell culture that precisely controls all physiological parameters to ensure cell optimal growth conditions for microscopic observation. This system not only maintains the required temperature and pH levels but also creates and sustains an environment tailored to experimental needs, keeping live cells in excellent condition during microscopic imaging processes– even for extended periods of days or weeks.

BMI-200 Microscope Incubator provides precisely controlled conditions including temperature, humidity, carbon dioxide (CO₂) concentration, and optional oxygen (O₂) levels, making it ideal for long-term live cell imaging. It can be perfectly compatible with multiple types of magnetic resonance imaging chambers, ensuring consistency and stability in experimental environments.

In addition, all parts of the incubator, including the main body, cover, humidifier and lens heater, as well as gas concentrations, can be precisely controlled and automatically recorded. The gas gradients can be programmed through a Computer-Controlled Program (CCP software) to ensure consistent and repeatable experimental conditions.

1. Automatic sensing mode

The humidity of cell culture can be maintained above 90%. The temperature control is achieved through three types of heating feedbacks.

External Mode

Using the optimal temperature control algorithm, the incubator automatically detects changes in the external temperature to minimize temperature deviations and ensure that the temperature inside the incubator is always optimized to the most suitable condition for cell growth.

Manual Mode

Users can set the temperature by themselves according to the experimental requirements, thus creating various environments for different purposes of researchers.

Sample Mode

By sensing the actual temperature of the sample, the temperature in the incubator is automatically adjusted to the most suitable state to ensure the best growth environment for cells.

Customizable living cell culture system for your own use

2. Easy to use

The incubator can be compatible with various microscopes and various types of culture chambers. It is small and is easy to assemble. It is controlled by a touch panel, wide 8-inch touch panel, making it easy and intuitive to operate. The sliding design of the sliding incubator cover is convenient for opening and closing. The fully open incubator cover provides full access for sample operation and maintenance.

 3. Constant temperature design

The incubator provides the best growth environment for cell culture by precisely controlling temperature, humidity, and pH value during time-lapse imaging. The cover and the chamber adopt high-efficiency heating systems to ensure internal uniform heat distribution. For enhanced thermal insulation and durability, the chamber is equipped with a heating plate to maintain constant temperatures, while the incubator cover made of double-layer glass effectively prevents heat loss.

4. Different types of incubator boxes and covers

BMI-200A: Standard model

The double-layer incubator cover is designed with good heat insulation performance. The top layer adopts tempered glass of Gorilla 6 Glass to ensure that it is not easy to break during use. The bottom layer is made of ITO heating glass, providing uniform heating effect.

The sample holder has a magnetic-fixed cover. The magnetic bonding method enables high sealing performance and better stability between the cover and the box.

The temperature is controlled by 3 heating feedback methods and is equipped with 3-channel fluid ports.

The sliding and stable fully-open cover design is convenient for users to operate. 

It is suitable for condensers with working distances of 26mm and 30mm.

BMI-200B: Lightweight Model

It is compatible with voltage stage. It is full open cover design.

BMI-200C: Universal Model

It can maintain the most suitable humidity. It is equipped with a built-in water tank to provide excellent humidity maintenance performance even when using commercial microplates. The water tank capacity is 40cc.

Long-term imaging can be performed with orifice plates.

5. Water tank sample rack

The water tank surrounding the sample holder improves and maintains humidity to prevent evaporation of the medium. It can be compatible with all types of cell culture consumables. The commercial orifice plates can be used without additional structures. The water tank capacity is 45cc.

The magnetic-fixed cover makes sample loading easier and more stable. When used with the magnetic-fixed cover, the lid of the dish can be removed for direct contact with the glass surface to form an effective sealing structure and reduce evaporation.

6. Temperature controller and gas mixer

Temperature Controller

Provide stable and precise sample temperature control required for long-term imaging. By using PID control, it can maintain the temperature of all heating components, including the incubator cover, incubator body, humidifier and lens heater.

• 3 types of heating control: external, sample (K type), manual induction feedback.
• 4 heating channels: incubator cover, main body, humidifier, lens heater.
• Simple cable connection with colored connector.
• Stable and persistent temperature distribution.
• Real-time chart and alarm function.
• Real-time thermal response.
• PID controls all parameters.

Gas Mixer

Provide CO₂, N₂ or O₂ gas with precise concentrations.

• It is equipped with three types of gas controllers.
• Solenoid valves and gas storage tanksare adopted to ensure uniform gas mixing
• The PID control system is used to adjust the gas concentration.
• Built-in air pump ensures stable gas flow.
• Quick connection is achieved through pipe fittings.

7. Humidifier

The humidifier capacity is 200cc. The humidifier generates moisture, helping the incubator maintain a relative humidity and prevent cell damage caused by water evaporation. The humidifier sensor controls the heating of water and CO2 gas passes through the heated water into the incubator. The airflow condition can be detected by observing the speed of bubbles.

• Maintain humidity saturation: Ensurethat the humidity in the incubator is always maintained at the best level.
• Maintain osmotic pressure:By preventing evaporation, the osmotic pressure of the culture medium is stabilized to avoid cell damage.
• Fast and accurate temperature control:The built-in heater and sensor are located in the water, capable of rapid heating and providing accurate temperature feedback.
• Backflow protection: Equipped with a backflow protection filter to prevent water from backflowing due to gas leakage or improper use.
• Convenient water supply:It can be easily replenished with an independent filling port without opening the lid, which is convenient to operate.

8. Remote trackpad

Android tablet PC provides an intuitive graphical interface to control all parameters required by the incubator system

• Control the system and all parameters through smartphones and other devices.
• Provide online troubleshooting.
• Using GUI (graphical user interface), intuitive and convenient to
• The GUI provides real-time temperature display and control.
• Data can be automatically saved and viewed in real time on the PC.
• Data is output to the PC via USB A cable.

Graphical user interface

• Intuitive and user-friendly: Easy to use, simplifying the operation process.
• Remote control: Remote management is achieved through an application on a smart phone or other mobile device.
• Real-time monitoring and control: Operators can adjust and monitor all parameters in real time anytime and anywhere.

9. Objective heater

To achieve high-resolution imaging, it is very necessary to control the temperature of the immersed objective. Oil, glycerol or water, as thermal coupling media, can conduct heat away from the sample. To prevent heat loss, an objective heater can be wrapped around the objective to generate and maintain an appropriate temperature. The silicone tape design can be adapted to various types of objectives.

To achieve high magnification and high-resolution imaging, a specially designed silicone heating tape is tightly wrapped around the objective to ensure there are no gaps, thereby effectively preventing heat dissipation from the sample temperature.

The flexible silicone heating tape can be adapted to all types of objectives.

The height of the main body of the incubator varies with the WD of the condenser used

(*Only applicable to the OX series)

Note: ● Standard Outfit, ○ Optional